Grubbs Catalyst Technology

The World’s Leading Ruthenium Metathesis Catalysts

Grubbs Catalyst® Technology

As the exclusive licensor of Grubbs Catalyst technology from Caltech, one of the world’s leading research institutions, Materia has a proud history of collaboration and innovation. Our catalysts enable unique chemical transformations leading to the creation of revolutionary drugs, functional materials, agrochemicals, surfactants and a wide range of other novel products with increased efficiencies and economics over existing manufacturing processes.

Materia’s successful commercialization of this groundbreaking olefin metathesis catalyst technology is owed to the inventions of Professor Robert H. Grubbs, our academic partner and collaborator, and our own industry-leading scientists and engineers who develop scalable commercial applications of the technology.

Originally discovered in the Caltech laboratories by Dr. Grubbs, our Grubbs Catalyst technology is a ruthenium olefin metathesis catalyst system that can unlock significant value for almost any olefin-based business or product. Compared with traditional catalytic processes, Grubbs Catalyst technology typically offers dramatic reductions in manufacturing steps, byproducts, and quantities of solvents and waste, significantly lowering capital and operating costs.

Materia is committed to the innovations enabled by Grubbs Catalyst technology. We lead the industry in olefin metathesis chemistry and enable innovative solutions to some of the world’s most challenging problems.

How the Technology Works

Grubbs Catalyst technology has transformed the landscape of synthetic chemistry. This robust catalytic technology provides a predictable, scalable, and user-friendly way to rearrange carbon-carbon double bonds, also known as olefins, to create molecules and materials with greater commercial utility.

The commercial significance of Grubbs Catalyst technology lies in the predictable and robust nature in which the catalyst rearranges a broad range of olefins to create higher value products and molecular structures.

Olefins are all around us; they are key building blocks for biological matter and one of the most common chemical compounds in the multi-trillion dollar petrochemical industry. At their most basic level, our robust catalysts allow these carbon atoms to more easily swap places, creating unique, structurally differentiated chemical compounds in addition to more efficient pathways to improve established products.

Core Features of Grubbs Catalyst Technology
  • Diverse family of catalysts enables reaction optimization.
  • Remarkable functional group tolerance with excellent stability and handling characteristics.
  • Olefin metathesis reactions are successful on scales ranging from milligram to multi-ton.
  • Green and cost-effective process: low catalyst loadings, solvent-free conditions, and high yielding processes with little waste.
  • Wide adoption and recognition of olefin metathesis by chemists across many fields, including petrochemicals, pharmaceuticals, and materials.
Incredible Application Range and User-Friendliness

As one of the most significant breakthroughs in catalyst technology in decades, Materia’s Grubbs Catalyst products are commercially proven with broad applicability across the entire chemical industry. In fact, 30 of the world’s 50 largest chemical companies and 40 of the world’s 50 largest pharmaceutical companies have used Grubbs Catalyst technology.

The predictable, scalable and robust nature of Grubbs Catalyst technology enables customers across a broad range of industries to use our technology to develop and manufacture innovative new products and streamline existing manufacturing operations.

Grubbs Catalyst Technology Powers Next-Generation Businesses

Materia’s IP portfolio is protected by over 350 issued and pending patents. In partnership with universities, our scientific advisors, and our founding scientist, Dr. Grubbs, Materia continues to advance the Grubbs Catalyst technology platform, dedicating significant R&D resources to further developing the catalysts, next-generation applications, and optimized manufacturing processes.

Due in part to Materia’s commercial progress, olefin metathesis is a widely adopted synthetic technique and powerful method for the efficient creation of broad classes of chemical structures. Grubbs Catalyst technology is transforming the specialty chemicals industry and we are committed to providing the volume and quality of catalysts necessary to support our growing customer base.

We support customers in a variety of industries by offering our catalyst products in research quantities through our exclusive distribution partner, Sigma-Aldrich. For larger scale orders, specialty catalysts, or chemical process development requests, please contact us directly.